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Amadeus study reveals the future traveller

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first_imgA new industry report, detailing the way people will travel by 2030, identifies six types of future travellers, including one that will structure entire holidays around how shareable their trip is on social media.Future Traveller Tribes 2030: understanding tomorrow’s traveller, released by Amadeus, identifies the six categories, or traveller tribes, as: social capital seekers, cultural purists, ethical travellers, simplicity searchers, obligation meeters and reward hunters.Amadeus Asia Pacific president Angel Gallego said today’s traveller should not be segregated into demographic groups of age, nationality or income.“With Asia Pacific set to lead global travel growth through to 2030, it is particularly critical for all providers, buyers and sellers of travel in the region to truly understand these emerging ‘traveller tribes’,” Mr Gallego said.Social Capital Seekers will base their entire holiday around how shareable it is on social media and will rely heavily on peer recommendations to validate their travel choices.Cultural Purists will seek holidays which force them outside of their comfort zone to experience an unfamiliar culture.Travellers who choose holidays based on moral grounds and include volunteering or eco-sustainable activities in their trip are known as Ethical Travellers.Simplicity Searchers will leave all the planning to a third-party and will seek bundled offers that ensure a safe and enjoyable trip.Driven by a specific travel purpose, Obligation Meeters are travellers who have a limit on time and budget and will opt for smart technology to remove the hassle of travelling.Finally, Reward Hunters are travellers who want to indulge in a premium holiday, rewarding them for the time and energy spent on their working life.The research was conducted through interviews and workshops with industry experts and consumers from relevant markets including Australia, China, India, Indonesia, Japan and South Korea.The report draws on consumer research by Future Foundation and takes a psychological approach to the idea rather than a demographic method.Future Foundation director Nick Chiarelli said the research not only demonstrates the changes in the type of experience travellers will seek in the future, but also how they will engage and buy within the industry.“Over the next 15 years the desire to share travel experiences will be profound, and so too the impact of sharing on inspiration and purchase trends will grow,” Mr Chiarelli said.“As consumers in developed markets approach a post-material era we expect a much greater focus on, first of all, experience, and second of all, ethics, both environmental and social, to significantly influence people’s travel choices and behaviours.”In June this year, a complementary report will be released examining how the industry can cater to the needs of each of the six traveller tribes identified in the report.Source = ETB Travel News: Brittney Levinsonlast_img read more

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first_img 2 Comments   Share   11 for 15 ! Welcome back Legend.— Tyrann Mathieu (@Mathieu_Era) February 15, 2018 Thrilled #Arizona will get to watch @LarryFitzgerald lead the @AZCardinals next season – us old geezers have to stick together! #BirdGang— John McCain (@SenJohnMcCain) February 15, 2018 (AP Photo/Ross D. Franklin, File) Top Stories If Larry Fitzgerald’s outing at the Pebble Beach Pro-Am was any indication of his NFL future, things didn’t look good for the Arizona Cardinals on Sunday.But on Wednesday, Fitzgerald decided it wasn’t time to make golf a full-time hobby. Instead, he announced his decision to return for a 15th season with the Cardinals. Following the retirements of former head coach Bruce Arians and quarterback Carson Palmer after the 2017 campaign, the 34-year-old wideout had a lot of attention directed his way in the offseason leading up to the decision. The 5: Takeaways from the Coyotes’ introduction of Alex Meruelo Us all offseason waiting for this news. 😄 pic.twitter.com/WHOasgBZ1j— Arizona Diamondbacks (@Dbacks) February 15, 2018With the NFL Draft and free agency on the horizon, Cardinals fans can breathe a collective sigh of relief for now knowing that No. 11 will suit up in 2018.center_img In 14 seasons, Fitzgerald has become the face of the franchise. His 15,545 yards and 1,234 receptions both rank third all-time in league history and he helped guide the Cardinals to their only Super Bowl appearance in 2008.The announcement was met with positive social media reactions. Former Cardinals kicker Phil Dawson retires Grace expects Greinke trade to have emotional impact Derrick Hall satisfied with D-backs’ buying and selling S/O to my guy @larryfitzgerald— Tony Jefferson (@_tonyjefferson) February 15, 2018 Wouldn’t be the same without out him…… pic.twitter.com/J7QIAhm9WD— Patrick Peterson /P2 (@P2) February 15, 2018last_img read more

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Liberty Globalbacked Belgian cable operator Telen

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first_imgLiberty Global-backed Belgian cable operator Telenet and Flemish commercial broadcaster Medalaan have signed a new deal that will see content from the VTM, 2BE, Vitaya, VTMKZOOM and JIM channels made available on Telenet’s Yelo TV multiscreen service.The new agreement, which will cover live and on-demand TV rights until 2017, will enable all Telenet Yelo TV users to watch Medialaan programmes on tablets, PCs and smartphones.Telenet said it hoped to be able to add the channels by the summer, with time-shifted viewing to be added later.“I’m very pleased with this agreement. TV viewing habits are changing dramatically, and that’s good news, because people watch TV more than ever,” said Peter Bossaert, CEO of Medialaan.“Together, Medialaan and Telenet will now seize the opportunity to develop this growth market further, and to update and innovate the existing television services at no additional cost for the viewer. We believe that cooperation between our companies creates value. We needed a little time for this, and have worked hard on it over the past few months. But I’m pleased that we’ve been able to make a clean break with the past and can look to the future once again.”last_img read more

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Investment in OTT content freetoair broadcastin

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first_imgInvestment in OTT content, free-to-air broadcasting, production outfits and sports rights form four pillars of Liberty Global’s new content investment strategy, according to president and CEO Mike Fries, with all four seen as ways to reinforce the company’s core distribution business.Following Liberty’s sale of its Chellomedia linear channel business to AMC, the company, far from turning away from content, has made a series of high-profile investments in different sectors in different markets – notably an investment in OTT rights for the My Prime streaming service in the Netherlands – designed specifically to counter Netflix; an investment in a 50% stake Flemish free-to-air broadcaster De Vijver and a 6% stake in UK commercial broadcaster ITV; and its acquisition of production outfit All3Media with Discovery. It has also invested in non-exclusive rights to Belgium’s Jupiler League through Belgium.Speaking to analysts after the company’s quarterly results this week, Fries said that Liberty’s content investments were “generally long term strategic moves”, with the partial exception of ITV, which is seen more as an opportunistic investment with some strategic benefits.Fries highlighted the success of the My Prime streaming service in the Netherlands, which is offered free of charge to premium cable subscribers and for €5.60 to basic subs. He said the service had been tried by over half of entitled subscribers. Fries said My Prime “pre-empts” Netflix, which launched in the Netherlands last year, by offering a similar SVoD product “for free”.On De Vijver, Fries said that the acquistion of a 50% stake would strengthen local subsidiary Telenet by providing access to content and production facilities that could be used to feed linear and SVoD channel offerings,  while its investment in All3Media provided access to a large catalogue of content.Fries said that Liberty’s investment in De Vijver and ITV also provided “a hedge” against the imposition of US-style retransmission rights, forcing distributors to pay for the right to transmit free-to-air channels on their networks.last_img read more

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Geordie Shore UK pay TV platform Virgin Media has

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first_imgGeordie ShoreUK pay TV platform Virgin Media has renewed its deal with Viacom, securing carriage for channels including MTV and Nickelodeon.The cable platform has secured the channels for an unspecified multiyear period. As well as the MTV, Comedy Central and Nickelodeon linear channels, the deal covers catch-up and box set rights.Virgin Media and Viacom, owner of Channel 5, have agreed a new multi-year programming deal in the UK and Ireland.The partnership ensures Virgin Media customers will continue to enjoy favourite networks like MTV, Comedy Central and Nickelodeon as well as bringing new channels, additional catch up TV and box sets to Virgin Media’s TV platform.The kids catch-up content will also include programming from Channel 5, the UK free-to-air channel that Viacom owns.Catch up titles include Geordie Shore (above) and Inside Amy Schumer from MTV and SpongeBob SquarePants and Paw Patrol from Nick.Viacom’s new streaming apps – MTV Play, Nickelodeon Play, Nick Jr. Play and Comedy Central Play – will also be available to Virgin’s subs.The Spike linear channel will also roll out on Virgin for the first time.David Bouchier, Chief Digital Entertainment Officer at Virgin Media said: “This agreement with Viacom means our customers will not just continue to have access to some of the very best TV from MTV, Comedy Central, Nickelodeon or the newly launched Spike, but can now enjoy even more programmes on demand – whether on TV or mobile.”Arran Tindall, SVP, Commercial and Content Distribution, for Viacom International Media Networks, added:  “We’re delighted to be partnering with Virgin Media to make content from all our branded networks available on every screen and both on-demand and on-the-go.”last_img read more

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The Chechen groups that threaten the security of t

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first_img The Chechen groups that threaten the security of the [Olympic] games are controlled by us, and they will not move in the Syrian territory’s direction without coordinating with us. Any coverage of Ukraine or Syria that ignores these facts disgraces itself. The New Message The new message I’ve been seeing lately is this: Obama is screwing up and making us look like wimps! We need to be powerful, not wimps! What that actually means is, “We should confront Putin and show him who’s tough! We’re still the biggest badass!” That kind of emotion, of course, leads toward war. Along with this emotionalism travels a peculiar fear found in empires: If we don’t rule the world, everything will break down into death and darkness. The Brits believed this not too long ago, as did many others, going back to the Romans and beyond. Here are a few passages from mainstream media that have caught my eye: “The collapse of the Pax Americana under Obama has freed up Russia and China to begin their campaigns of territorial expansionism.” Last year, lots of powerful groups tried to get a war going in Syria. It seemed to me that the necessary ground work hadn’t been done and that they might not be able to pull it off. Thankfully, that’s how it happened. And by “necessary ground work,” I’m not referring to the military operators the US government had in Syria for a year or two prior; I’m talking about making the American populace eager for a new war. That’s a crucial and often ignored factor. What has been catching my eye the past week or so is a new series of efforts to stir up war fever in the US, and I’d like to give them some coverage. Since the mainstream ‘news’ in the US has become almost completely trivialized and neutered, I think it’s important for the rest of us to fill the gap as best we can. First Points Before I get to what I see as the new war propaganda, I want to point out what all the ‘respectable’ voices are ignoring: This leaked recording (embedded in video) is from February 6 – before the deposing of the Ukrainian boss that started the current mess. In it, you’ll hear US State Department officials deciding who should be the new boss of the country, once they’ve had their way. This is clear, uncontested proof that it was the State Department who got things going in the Ukraine. Whatever we think of Putin, it must be acknowledged that these guys stirred it up. This video contains conversations of high Turkish officials planning a fake attack to start a war with Syria. “Russia has taken over Crimea and threatens further aggression. Now is the time to act…” “Putin has given speeches almost identical to Hitler’s 1938 Berlin address.” “Instead of a post-American world ushering in a stable multilateral order, it will revert back to a chaotic Lord of the Flies situation.” Leaked documents have shown that the Saudis are pushing very hard for a war in Syria (intended, presumably, to weaken Iran). They go so far as to tell Putin that they control terrorist groups, including those who could attack in both Russia and in Syria. (Think about that!) Here’s a direct quote from what they said to Putin: This leaked recording (embedded in video) features an Estonian foreign minister talking to an EU official. In it, he says that the snipers who were said to be killing on Putin’s orders were actually working for the people the US was putting into power. “Fear That Obama Will Let Russia Seize Control Of Internet.” To this I’ll add one more thing: Millions of people currently believe that Russian troops have invaded the Crimea, which is completely false. Honestly, I’m not sure that this will work. However hungry the military-industrial complex may be, Joe and Jane Average are just not eager for another war. And I think Putin’s smart enough to withhold any Pearl Harbor-like attacks. Even a big terrorist attack might only prove that the intel state has failed again. I’m not sure that people can maintain an endless blind faith in Jack Bauer; at some point, they will say, “That was only a TV show.” That said… That said, “Washington Worship TV” continues and they’re still working toward war. Obama just paid a call on the Saudis, who remain desperate for their war in Syria. They’re so desperate, in fact, that they’re working with the Israelis on it. (War makes for strange bedfellows.) And on his way to Arabia, Obama called on the Pope. What these meetings were really about, who knows. Backroom deals between intel agencies take place all the time. No one’s going to admit what the conversations are about, but one can certainly imagine that a deal was underway to give Putin the Crimea in return for the war in Syria that NATO and its friends wanted. The leaks mentioned above (especially the Turkish leak) may have delayed matters, but since it has never appeared on “the news,” most people have never heard about it. Perhaps the push for war in Syria will continue. But, it may be that NATO and their allies have given up on their war in Syria and are trying to punish Putin for standing in their way. (It’s likely that Russia was the source of those leaks.) That would involve bloodshed in the Ukraine… as if the Ukrainians haven’t suffered enough in the past eighty years. The Bottom Line The bottom line is that several groups are very eager for a new war. Toward that end, they’re working to stir up emotions. Rationally convincing people to kill and be killed, of course, isn’t terribly effective. What we have to do now is to keep our heads and be a voice of reason for our friends and neighbors, even if they don’t like it. War is not salvation; it’s hell. Paul Rosenberg FreemansPerspective.comlast_img read more

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Order Postmates It Might Arrive Via an Autonomous Ford

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first_imgDelivery Learn how to successfully navigate family business dynamics and build businesses that excel. The automaker is teaming up with Postmates for autonomous delivery trials. Add to Queue Order Postmates? It Might Arrive Via an Autonomous Ford. Next Article 2 min read Image credit: via PC Mag Free Webinar | July 31: Secrets to Running a Successful Family Businesscenter_img In the future, takeout, groceries and other things you order through the delivery startup Postmates might arrive via a self-driving Ford.The automaker is teaming up with Postmates for autonomous delivery trials. As part of this partnership, the companies plan to conduct pilot programs throughout the year to understand “how self-driving technology could change the delivery experience for consumers, enable brick-and-mortar retailers to reach new customer bases, and transform the way commerce moves,” Ford’s Vice President of autonomous vehicles and electrification Sherif Marakby wrote in a blog post.Postmates is an app and web-based service that connects customers with “local couriers who can deliver anything from any store or restaurant in minutes,” the company says on its website. Originally launched in its hometown of San Francisco, the service is now available in more than two dozen states and the District of Columbia (to see if it’s available in your area, head here).The companies hope this partnership leads to more efficient deliveries and helps consumers connect with small and local businesses in their area, according to Marakby.”The way commerce is moving around in cities is dramatically changing, and emerging technology will undoubtedly have an impact on the future of on-demand delivery,” Marakby wrote. “With the knowledge we’ll gain from our partnership with Postmates, we anticipate we’ll be able to better deploy self-driving technology in a way that can help people get what they need faster, while also supporting local businesses that are a big part of communities around the world.”Last year, Ford teamed up with Domino’s to carry out a self-driving pizza delivery experiment in Ann Arbor, Mich., using Ford’s Fusion Hybrid vehicles for deliveries. January 10, 2018 This story originally appeared on PCMag Reporter Angela Moscaritolo Register Now » –shareslast_img read more

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Jony Ive Reportedly Felt That Tim Cook Wasnt Interested in Design

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first_img Next Article –shares Steve Dent This story originally appeared on Engadget Jony Ive Reportedly Felt That Tim Cook Wasn’t Interested in Design Free Webinar | July 31: Secrets to Running a Successful Family Business 3 min read Image credit: Justin Sullivan/Getty Images via engadget Register Now » Jony Ive’s departure was made official last week, but may have begun years ago because of Apple’s shift in focus from design to operations, according to the WSJ and Bloomberg. Citing multiple unnamed sources, the reports stated that Ive was “dispirited” by Tim Cook’s lack of interest in design, especially considering the close synergy he shared with former Apple CEO Steve Jobs. At the same time, Ive was coming into Apple’s offices much less often than before, “straining the cohesion central to product development,” the WSJ stated.Ive reportedly started showing up at Apple’s offices less often after the release of the Watch. Rather than an iPhone peripheral, Ive saw it was a fashion accessory, clashing with Apple executives over how to position it. The resulting device, at $349, sold only 10 million units (a quarter of the forecast), while “thousands” of copies of the $17,000 gold version went unsold, according to the WSJ.Much like many Apple fans, Ive was supposedly frustrated with the change in company culture from the one — established by he and Jobs — where design ruled. He was not only disappointed by the fact that Tim Cook “showed little interest in the product development process,” but also that Apple’s Board was increasingly filled with directors that had no experience in Apple’s business.Ive was promoted to Chief Design Officer shortly after the launch of the Watch, but only came to the office a couple of days a week, according to Bloomberg. Meetings were often moved to San Francisco where he lived, and even to hotels, homes of employees and other venues. “The team craved being around him,” said a WSJ source close to Apple leadership at the time. “He’s engaging. Him being around less was disappointing.”Ive created numerous iconic projects with Apple, often as a result of discussions, debates and arguments with Jobs. That includes iconic products like the iPhone, iPad, iPod, MacBook Air, Apple Watch and even Apple’s new headquarters. However, recent products like the HomePod and iPhone X models have enjoyed less success, and Apple recently killed its AirPower charging pad, which Ive imagined as a catchall for Apple devices. According to the WSJ, however, “engineering tests found it behaved more like a dorm-room hot plate.”Now his new design firm, “LoveFrom,” will reportedly be paid “millions of dollars a year to continue to work with Apple,” the WSJ said. That could give Ive the best of both worlds, only working on the stuff he wants for Apple without having to deal with internal politics. Add to Queue Ive was often absent from key product meetings, according to the WSJ. July 1, 2019 Learn how to successfully navigate family business dynamics and build businesses that excel. Applelast_img read more

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The Driver Who Sued Uber Slams Offensive Settlement

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first_imgClass Action Lawsuits Image credit: Reuters | Lucy Nicholson The Uber driver behind the lawsuit that threatened the company’s business model is now objecting to settling the case.In April, Uber announced that it had reached a $100 million settlement agreement in a court case that had gone on for three years. Douglas O’Connor filed suit against the company in 2013, claiming that Uber had misclassified its drivers as independent contractors and that they should be employees.The culmination of the case was announced in April with a $100 million settlement for drivers in California and Massachusetts.But in a court filing on Monday, O’Connor is now objecting to the settlement that bears his name, saying that it shortchanges drivers of billions.O’Connor said:”I am compelled to submit this declaration objecting to the class action settlement on behalf of myself and on behalf of the hundreds of thousands of other Uber Drivers in the State of California — and throughout the Country — who were at first given hope and a voice by the lawsuit bearing my name but now feel utterly betrayed and sold-out by an unjust settlement result that only benefits Uber.”In his objection, O’Connor claims that he never saw a copy of the settlement before Uber announced it in April. After it was announced, he claims that he was pressured into quickly signing the 100-page document.After reviewing the settlement, O’Connor doesn’t believe that the agreement is in the best interests of Uber drivers.He wrote:”Having now had the full opportunity to review the O’Connor settlement agreement, it is apparent that under the agreement, Uber drivers are being sold out and shortchanged by billions of dollars while sacrificing the determination of their classification as employees.”He initiated the case against Uber three years ago because he felt that the company misclassifying its drivers was “the most significant hazard to the economy and public safety,” he says. The settlement doesn’t answer that question.O’Connor says in the objection:”Unfortunately, the magnitude of this generational threat was given short shrift in the O’Connor class action as almost no meaningful discovery or depositions were taken, but where the average Uber driver will now receive an offensive settlement worth less than a tank of gas. I cannot in good conscience support this disastrous settlement agreement.”Uber declined to comment on the objection. Shannon Liss-Riordan, his former attorney, said that the things O’Connor is saying “are simply not true.”Liss-Riordan wrote in an email to Business Insider:”The case was at risk of being gutted by the Ninth Circuit and we made the choice we did, in consultation with our clients. Mr. O’Connor was not a lead plaintiff, and had not been certified to represent the class, but I kept him in the loop because the case bore his name. I believe the settlement was in the best interests of the class, in light of the risk we faced if having the case pulled out from under us by the Ninth Circuit. But if the court disagrees and thinks the settlement should not go forward for some reason, I would be more than happy to plow forward with it and do what I need to do.” Next Article May 17, 2016 Add to Queue 2019 Entrepreneur 360 List Biz Carsoncenter_img 3 min read This story originally appeared on Business Insider –shares The Driver Who Sued Uber Slams ‘Offensive’ Settlement Apply Now » The only list that measures privately-held company performance across multiple dimensions—not just revenue.last_img read more

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Samsung Mobile Recovery Suffers Blow as Galaxy Notes Catch Fire

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first_img Samsung Mobile Recovery Suffers Blow as Galaxy Notes ‘Catch Fire’ –shares Image credit: Reuters | Kim Hong-Ji Next Article The recovery in Samsung Electronics Co. Ltd.’s mobile business suffered a blow on Thursday as reports of exploding batteries forced the firm to delay shipments of Galaxy Note 7 smartphones, and knocked $7 billion off its market value.Investors drove the stock to two-week lows after the global smartphone leader told Reuters late on Wednesday the shipments had been delayed for quality control testing, and that shipments to South Korea’s top three mobile carriers had been halted.Faults with the new premium flagship device could deal a major blow to the South Korean giant, which was counting on the Galaxy Note 7 to maintain its strong mobile earnings momentum against Apple Inc.’s new iPhones expected to be unveiled next week.”This is some major buzz-kill for Samsung, especially given all of the hard-earned excitement that products like the Note 7 have been garnering lately,” IDC analyst Bryan Ma said.”The pending Apple launch puts all the more pressure for them to contain this quickly. The timing of this couldn’t have been worse.”Samsung did not comment on what problem it was trying to address or whether other markets were affected besides South Korea.Sister company Samsung SDI Co. Ltd. said that while it was a supplier of Galaxy Note 7 batteries, it had received no information to suggest the batteries were faulty.Several people posted images and videos of charred Galaxy Note 7s online and said their phones had caught on fire.”Be careful out there, everyone rocking the new Note 7, might catch fire y’all,” one user said in a YouTube clip showing a burnt Note phone. It was not immediately possible to confirm the veracity of the clip.Samsung’s shares, which hit a record high of 1.694 million won last week, fell 2 percent, and Samsung SDI tumbled 6.1 percent, versus a 0.1 percent fall for the broader market.Several South Korean media reports, without citing direct sources, said Samsung will soon announce a plan to recall affected Note 7 phones and replace their batteries as opposed to giving the users a new device. A Samsung spokesman declined to comment on the reports.Damage controlLast year, production problems for the curved displays for the Galaxy S6 edge model resulted in disappointing sales, and Samsung risks a repeat this year if it cannot address the Galaxy Note 7 problems quickly.Its mobile profit is on track to post annual growth for the first time in three years, thanks to robust sales of the Galaxy S7 and S7 edge devices that it launched in March to critical acclaim.The Galaxy Note 7 received similar praise, raising expectations for strong sales in the second half. Samsung said in August demand for the new handset, priced at 988,900 won ($882) in South Korea, was far exceeding supply, pushing the firm to delay the launch in some markets.HDC Asset Management fund manager Park Jung-hoon said it now appeared inevitable that Samsung’s smartphone average selling price and profits would miss lofty second-half expectations.”Apple is supposed to show off the iPhone 7 next week and this issue has emerged, so the current state of things do not look good,” he said.Though a components pick-up will buttress overall profits, Park said mobile operating profit might decline by up to 200 billion won for July-September.The mobile division accounted for about 54 percent of Samsung Electronics’ January-June operating profit of 14.8 trillion won.Hyundai Securities said in a report that the Galaxy Note 7’s problems should be resolved within a “few weeks”.The brokerage retained its third-quarter operating profit forecast of 8.5 trillion won.(Reporting by Se Young Lee; Editing by Stephen Coates and Simon Cameron-Moore) 2019 Entrepreneur 360 List A model demonstrates iris recognition function of Galaxy Note 7 new smartphone. Faults with the new premium flagship device could be a major setback for the South Korean giant. This story originally appeared on Reuterscenter_img The only list that measures privately-held company performance across multiple dimensions—not just revenue. 4 min read Reuters Add to Queue Samsung Galaxy September 1, 2016 Apply Now »last_img read more

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AfricanAmericans in major US cities more likely to live in trauma deserts

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first_imgReviewed by James Ives, M.Psych. (Editor)Mar 11 2019African-Americans in major U.S. cities are significantly more likely to live in “trauma deserts” with limited access to advanced emergency medical care, according to new research from the University of Chicago Medicine. The study also shows the academic medical center’s new Level 1 Trauma Center led to a seven-fold reduction in Chicago’s access disparity.The findings, published March 8 in the Journal of the American Medical Association’s Network Open, are the first to be released about the impact of UChicago Medicine’s adult Level 1 Trauma Center. Adult trauma services at the hospital began in May 2018.”So much of the advocacy for the trauma center was framed in terms of racial equity,” said Elizabeth Tung, MD, MS, a primary care physician and instructor of medicine at UChicago Medicine who was the paper’s first author. “But we realized no previous studies had addressed trauma access through the lens of race/ethnicity – not just looking at Chicago, but comparing our city to other communities as well.”The research team examined access to trauma care in Chicago, New York and Los Angeles using a geospatial analysis that compared the location of designated trauma centers with the racial and ethnic composition of the cities’ census tracts. The project included only Level 1 and Level 2 Trauma Centers, which are able to provide medical care to patients with the most serious injuries.Using a standard established in previous research from colleagues at other hospitals, the team defined a “trauma desert” as any urban community that is at least five miles away from advanced trauma care. While many suburban and rural communities are significantly further away from trauma care, Tung said dense urban communities must be assessed differently.”Five miles in a rural area is probably five minutes away, but in an urban area that same distance could be 15 minutes or it could be two hours away – it entirely depends on traffic congestion,” Tung said. “The kind of care in urban trauma also differs from that in rural areas – the types of trauma are generally different, the patient volume is higher and the injuries are more severe.”Trauma centers provided advanced emergency medical care for patients with critical injuries, including those from motor vehicle accidents, falls, shootings and stabbings.Related StoriesAMSBIO offers new, best-in-class CAR-T cell range for research and immunotherapyResearch sheds light on sun-induced DNA damage and repairHome-based support network helps stroke patients adjust after hospital dischargeIn Chicago, the team found that 73 percent of census tracts with a mostly black population were located in trauma deserts. Until UChicago Medicine’s trauma center opened 10 months ago on its Hyde Park medical campus, residents of those communities had 8.5 times higher odds of being farther away from trauma care than people living in the city’s white-majority census tracts. The new trauma center reduced this disparity by nearly 7-fold, to 1.6 times.”Since we opened the trauma center nearly one year ago in May, the disparity in access to adult trauma care has been significantly lessened for African-Americans in Chicago,” said Selwyn Rogers, Jr., MD, MPH, a professor of surgery and the director of UChicago Medicine’s trauma center, which has treated more than 2,000 trauma patients.In New York City, just 14 percent of African-American communities were located in trauma deserts. In Los Angeles, 89 percent of African-American communities were located in trauma deserts, although very few census tracts in Los Angeles remain predominantly African-American. The team said Chicago’s Hispanic and Latino communities were also more likely to be farther from trauma care than those living in white communities. The Hispanic and Latino disparity was not present in New York or Los Angeles.”Even though we had a sense that this was a racially divided issue, the data confirmed that this was the case in a significant way. It was pretty startling,” said Monica Peek, MD, MPH, an associate professor of medicine and health disparities researcher who was the senior author on the paper.UChicago Medicine has provided pediatric trauma care at Comer Children’s Hospital since 1990, but previously ended its adult trauma program in 1988 before announcing it would resume the service in 2015 in response to community requests. The hospital built a new adult emergency department, which opened in late December 2017. Adult trauma services launched about five months later, following regulatory approval.The researchers said they hope their findings highlight the lingering impact of structural inequality in U.S. cities. They said planning for new trauma centers, which require a significant financial investment, should include an assessment of how a new facility can help address racial equity. Source:https://www.uchicagomedicine.org/forefront/trauma-articles/2019/march/race-and-trauma-desert-researchlast_img read more

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Biologists analyze available methods of targeted drug delivery to malignant tumors

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first_imgReviewed by James Ives, M.Psych. (Editor)Apr 9 2019A team of biologists from Sechenov First Moscow State Medical University and Lobachevsky University (Nizhny Novgorod) analyzed available methods of targeted drug delivery to malignant tumors. Individual approaches to cancer therapy limit the influence of drugs on healthy tissues and reduce side effects. The results of the study were published in the Cancers journal. The research was supported by a grant issued by the Ministry of Science and Higher Education .The difference between healthy tissue and a tumor lies in the structure of its vasculature and changes in metabolism. In tumors blood vessels are formed chaotically, have different shapes and diameters, and exhibit closed ends and protrusions. The structure of lymphatic vessels also changes. A tumor and its vasculature grow at different speed causing oxygen and nutrients deficiency. The structure of the tissue and its metabolism changes, as well as the profile of molecules on the surface of tumor cells, and the cancer progresses. Taking these facts into consideration, one can develop methods of target antitumor drugs delivery without affecting healthy cells and causing unnecessary side effects.Currently, there are three main ways of targeted drug-to-tumor delivery: passive targeting that takes into account the structure of the vessels; active targeting in which an antitumor drug binds with a molecular target; and cell-mediated targeting.Due to the peculiarities of tumor vessels, large molecules can enter them relatively easily and accumulate in the tumor tissue. This phenomenon is known as enhanced permeability and retention effect, and passive drug targeting is based on it. However, this delivery method doesn’t always guarantee a desired effect. To increase its efficiency, individual therapies are developed on the basis of tumor characteristics. For example, the size of an agent may be optimized accordingly.Related StoriesDon’t Miss the Blood-Brain Barrier Drug Delivery (B3DD) Summit this AugustNew class of cancer-killing agents shows promise in destroying cancer stem cellsCommon cold virus strain could be a breakthrough in bladder cancer treatmentActive targeting complements the passive method. It increases the accumulation of a drug in tumor and the time of its retention. In their earlier work the team presented a multifunctional complex that leads to a synergistic effect of combined chemo- and radiotherapy agents. The base of the complex is a luminescent nanoparticle that contains a radioactive isotope 90Y used in radionuclide therapy. On the surface there is a bound highly active fragment of exotoxin A obtained from Pseudomonas aeruginosa (PE40). The complex binds with a marker protein of cancer cells, and its toxic agents affect the tumor. This treatment method works because tumor cells have different metabolism and molecular profiles than the cells of healthy tissues.Certain types of cells are able to penetrate tumor tissues and therefore can also be used to deliver drugs. Cell-mediated targeting extends the washout period, controls the release of the drug, and reduces general toxicity and side effects. This method has its limitations, but it is also very promising.”Having a choice between various treatment methods that take into account molecular and structural characteristics of a tumor and being able to adjust drug administration regime means approaching the goals of personalized medicine,” said Irina Balalayeva, a Candidate of Biological Sciences, Dean of the Department of Biophysics of the Institute of Biology and Biomedicine at Lobachevsky University, and a senior research associate of the laboratory of nanotheranostics at the Institute of Molecular Medicine, Sechenov Moscow State Medical University.Understanding the processes of nutrients and metabolic products transportation within a tumor, the peculiarities of its structure, and its interaction with immune system cells can help increase the efficiency of antitumor drug delivery and cancer treatment.Source: https://www.sechenov.ru/eng/news/141366/last_img read more

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Eccentric exercises could help fatigued dancers prevent injury improve jump performance

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first_imgOur study suggests fatigued dancers may lack the strength to control their legs when absorbing the forces from the landing, affecting the technique and artistry of their jump as well as increase risk for injury. Targeted eccentric exercises could enable them to control their movements when they’re tired. This may help them consistently perform the jump in good form as well as reduce the risk of injury.”Danielle N. Jarvis, PhD, ATC, senior author of the study and assistant professor of kinesiology at California State University Northridge Researchers studied 17 professional ballet dancers who performed 10 sauté jumps before and after a protocol designed to mimic a ballet class or rehearsal. They used a 12-camera motion capture system and force plates to collect three-dimensional movement data while the dancers performed the jumps. The researchers determined that the dancers’ ankles flexed more deeply upon landing when they were fatigued (30.32 degrees) compared to before they were tired (28.88 degrees). Fatigue also lessened the peak landing forces, meaning the dancers landed softer. The force plates determined they landed with 1.72 times their body weight when fatigued, vs. 2.13 times their body weight before they were fatigued. The motion capture system showed that while the dancers achieved the same jump height, they did not point their toes as proficiently when fatigued.Related StoriesDoing more harm than good: Scientists uncover harmful effects of dietary supplementsResearchers identify new sarcoma familial risk gene’Text neck’ may be causing bone spurs in young peopleBased on their findings, the researchers surmise that eccentric exercises could help lengthen and strengthen the calf muscles, counteracting the effects of fatigue. Eccentric muscle contractions occur in the lowering phase of a traditional movement (e.g. lowering into a squat, or lowering the arms after a biceps curl), causing a muscle to lengthen rather than shorten. One such exercise involves standing on both toes and then lowering one foot in a very slow, controlled manner, rather than letting the heel come down quickly.”Athletic trainers can work with dancers to identify eccentric movements they can do to achieve better control and jump more effectively,” said Dr. Jarvis. “We believe that if dancers are better able to control – and not collapse into – the landing, they are more likely to use the proper technique and may be less likely to get injured.” Source:National Athletic Trainers’ Association (NATA) Reviewed by James Ives, M.Psych. (Editor)Jun 26 2019Exercises that lengthen leg muscles may help dancers counteract fatigue, preventing injury and allowing for a more perfected jump technique, suggests research being presented at the National Athletic Trainers’ Association (NATA) 70th Clinical Symposia & AT Expo.Researchers studied how well trained ballet dancers performed the classic sauté jump – a vertical jump with feet pointing down – before and after becoming fatigued by dancing. When tired, the dancers’ form suffered, both in air and on landing.Dance is a very physically demanding activity and injuries are common. However, there is limited research examining the biomechanics of dance movements and the effects of fatigue on dance performance and technique. The researchers sought to assess fatigue and resulting movement patterns to shed light on how athletic trainers can better work with dancers to prevent injuries.last_img read more

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Higher levels of physical activity not linked to greater volume or activity

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first_img Source:University of GranadaJournal reference:Acosta, F.M. et al. (2019) Association of objectively measured physical activity with brown adipose tissue volume and activity in young adults. Journal of Clinical Endocrinology and Metabolism. doi.org/10.1210/jc.2018-01312. Studies that analyze the effect of regular physical activity, from a molecular point of view, are necessary to help us understand the mechanisms that mediate the therapeutic effects of exercise in humans.”Francisco Miguel Acosta Manzano, doctoral student in Biomedicine, UGR’s International School for Postgraduate Studies Reviewed by James Ives, M.Psych. (Editor)Jul 5 2019A study conducted by researchers from the University of Granada (UGR) has found that, in contrast to scientific thinking to date, higher levels of physical activity are not linked to a greater volume or activity of brown adipose tissue (BAT). BAT is a thermogenic organ that burns glucose and fats, releasing the energy that is produced in the form of heat.When BAT is activated, it consumes glucose and lipids, partially preventing them from being stored in other tissues, such as white adipose tissue (or common fat), which is located, for example, around the abdomen.Over the last decade, several studies have unequivocally confirmed the presence of BAT in human adults. BAT is a thermogenic organ equipped to dissipate energy in the form of heat through the so-called “uncoupling protein”. Therefore, it has been postulated that generating a greater volume of BAT, and increasing its activity, could be a potential strategy for combatting obesity and associated comorbidities, such as type 2 diabetes.Researchers have tended to channel their efforts into identifying strategies to help improve BAT function safely over the long term. On this premise, previous studies have suggested that raising levels of physical activity could be an effective strategy for increasing the volume and activity of BAT. However, the data from extant studies conducted on humans are both scarce and contradictory.In this new study, published in the Journal of Clinical Endocrinology and Metabolism, the UGR scientists investigate, for the first time, the link between objectively-measured levels of physical activity and the quantity and activity of BAT. The latter are measured by means of proton-emission tomography combined with computed tomography (using a radiopharmaceutical known as18F-Fluorodeoxyglucose). This study was performed on a sample of sedentary young adults, whose BAT was measured (the largest cohort of its kind to date). The sample comprised 87 women and 43 men, with an average age of 22 years.Related StoriesLiver fat biomarker levels linked with metabolic health benefits of exercise, study findsResearchers to examine if a ‘snacktivity’ approach to physical activity is effective in improving healthMobile phone app may help boost and maintain physical activity in womenThis study was part of the ACTIBATE (Activating Brown Adipose Tissue Through Exercise) project (http://profith.ugr.es/actibate), which was implemented by the University of Granada during 2014-2017. It was funded by Spain’s then-Ministry of Economy and Competitiveness, via the Health Research Fund of the Carlos III Institute of Health (PI13/01393).No link identifiedThe authors of the article observed that there was no link between the levels of physical activity and the volume and activity of BAT, even after adjusting the analyses for covariables that could be influencing the results. Nor was the time spent being sedentary associated with the volume and activity of BAT, they noted. The authors concluded that, although physical activity is one of the main interventions recommended in the prevention of chronic diseases such as obesity and type 2 diabetes, other mechanisms beyond an increase in the volume and activity of BAT could be mediating its beneficial metabolic effects. These findings contradict the results of previous studies, and call into question the role of exercise in improving BAT function.last_img read more

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New sensor for measuring electric field strength

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Schematics of the sensor: the moveable and the fixed grid. Credit: TU Wien Accurately measuring electric fields is important in a variety of applications, such as weather forecasting, process control on industrial machinery, or ensuring the safety of people working on high-voltage power lines. Yet from a technological perspective, this is no easy task. A moveable grid made of silicon is displaced in an electric field, relative to another grid, which is fixed. Credit: Vienna University of Technology Journal information: Nature Electronics Tiny new sensor — compared to a one-cent-coin. Credit: TU Wien Team develops new semiconductor processing technology Explore further More information: Vittorio Ferrari, Distortion-free probes of electric field, Nature Electronics (2017). DOI: 10.1038/s41928-017-0013-9 Provided by Vienna University of Technology This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. The sensor developed by the team at TU Wien is made from silicon and is based on small, grid-shaped silicon structures measuring just a few micrometres in size fixed to a small spring. When the silicon is exposed to an electric field, a force is exerted on the silicon crystals, causing the spring to compress or extend slightly.These tiny movements are made visible via an optical solution—an additional grid located above the movable silicon grid is lined up so precisely that the grid openings on one grid are concealed by the other. When an electric field is present, the structure moves slightly out of perfect alignment with the fixed grid, allowing light to pass through the openings. This light is measured, from which the strength of the electric field can be calculated by an appropriately calibrated device.Prototype achieves impressive levels of precisionThe new silicon sensor does not measure the direction of the electric field, but its strength. It can be used for fields of a relatively low frequency of up to one kilohertz. “Using our prototype, we have been able to reliably measure weak fields of less than 200 volts per metre,” says Andreas Kainz. “This means our system is already performing at roughly the same level as existing products, even though it is significantly smaller and much simpler. Other methods of measurement are already mature approaches—we are just starting out. In the future, it will certainly be possible to achieve significantly better results with our microelectromechanical sensor.” Citation: New sensor for measuring electric field strength (2018, January 25) retrieved 18 July 2019 from https://phys.org/news/2018-01-sensor-electric-field-strength.html In a break from the design principle employed by all other measuring devices to date, a research team at TU Wien has now developed a silicon-based microelectromechanical (MEMS) sensor. Devised in conjunction with the Department for Integrated Sensor Systems at Danube University Krems, this sensor has the major advantage that it does not distort the very electric field it is currently measuring. An introduction to the new sensor has also been published in the electronics journal Nature Electronics.Distorting measuring devices”The equipment currently used to measure electric field strength has some significant downsides,” explains Andreas Kainz at TU Wien. “These devices contain parts that become electrically charged. Conductive metallic components can significantly alter the field being measured, an effect that becomes even more pronounced if the device also has to be grounded to provide a reference point for the measurement.” Such equipment also tends to be relatively impractical and difficult to transport. read more

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YouTube adds student plans in latest attempt to challenge Hulu Spotify and

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first_img (c)2018 USA TodayDistributed by Tribune Content Agency, LLC. Credit: CC0 Public Domain On Tuesday, YouTube announced it would be adding new student options for its YouTube Music service as well as YouTube Premium, its commercial-free version of YouTube.YouTube Music, a rival to Spotify and Apple Music (both of which already offer student plans), will be available to college students for $4.99 a month, down from its regular rate of $9.99 a month. Users of YouTube Music can download songs and albums for offline listening, listen to music even if you leave the YouTube app and can stream music ad-free.YouTube Premium, a Netflix and Hulu rival, includes YouTube Music’s benefits and adds the ability to watch regular, nonmusic YouTube videos without ads plus includes access to YouTube Originals such as “Cobra Kai,” a spinoff of “The Karate Kid” films.YouTube Premium runs $6.99 a month with the discount, down from its normal rate of $11.99 a month. Those who sign up for YouTube Premium by Jan. 31 will be able to get it for $5.99 a month.While the new discounts are sure to please YouTube lovers, for many Spotify’s student deal may still be the better video and music streaming option. That deal is not only cheaper at $4.99 a month but includes Spotify’s commercial-free Premium service, a subscription to Hulu (with limited commercials) and bundles in Showtime.Apple Music, which includes access to Apple’s original series as well as commercial-free music downloading and streaming, is also $4.99 a month for college students.YouTube’s new student offerings are available today to U.S. students at an accredited college or university. Hoping for a student plan for YouTube? You now can have one. YouTube revamps streaming music servicecenter_img Explore further Citation: YouTube adds student plans in latest attempt to challenge Hulu, Spotify and Apple Music (2018, November 28) retrieved 17 July 2019 from https://phys.org/news/2018-11-youtube-student-latest-hulu-spotify.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more

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